The Cell Biology Group at the Pablo de Olavide University (UPO) is working on research in the Andalusian Centre for Developmental Biology. Its research is based on different aspects of Coenzyme Q (CoQ) biology from its synthesis and rare mitochondrial diseases...
Imperial College London (ICL) is one of the UK’s leading research universities (currently ranked 2nd in the QS World University Rankings 2025). Imperial is a science-based university with an international reputation in teaching and research, focusing on science,...
Coenzyme Q10 is the main antioxidant in cell membranes and lipoproteins protecting them against oxidation and preventing cell death by ferroptosis or atherosclerosis.
Purple bacteria (PPB) are rich in coenzyme Q10 the main antioxidant in cell membranes and an essential component of the mitochondrial electron transport chain. The increase in coenzyme Q10 in plasma protects cholesterol vehiculated by lipoproteins against oxidation and thus, protects against atherosclerosis, the accumulation of cholesterol in the arteries.
Coenzyme Q10 is also the main antioxidant in cell membranes protecting them against oxidation and cell death by apoptosis or by ferroptosis. This protection can prevent many diseases and even senescence preventing cell damage.
In the case of aging, high coenzyme Q10 levels in plasma are related with higher physical capacity whereas low levels are related with initial steps in cognitive dysfunction. This effect probably depends on the protection of vascular endothelium.