Within the Purple4Life project, Nofima contributes its expertise in fish feed formulation and production, fish nutrition and the evaluation of how functional ingredients such as purple phototrophic bacteria (PPB) influence fish performance, health, welfare and product...
Within the Purple4Life project, Comenius University, Faculty of Medicine (UNIBA), based in Bratislava, Slovakia, is an active participant in this European initiative. Our team contributes expertise in mitochondrial medicine, antioxidants, and oxidative stress. What is...
Within the Purple4Life project, the Université catholique de Louvain (UCLouvain) contributes its expertise in human nutrition, formulation science, and clinical research to support the translation of purple bacteria–based ingredients into nutritionally effective and well-accepted solutions.
UCLouvain’s work focuses on ensuring that key compounds derived from purple bacteria—proteins and essential amino acids, coenzyme Q10 (CoQ10), and carotenoids—are not only present in the final products, but are bioavailable, stable, and suitable for human intervention studies.
What is being developed: formulation strategies for bioavailability
One of our research activities consists in the optimization of formulations designed to enhance the digestion, absorption, and metabolic availability of purple bacteria–derived nutrients and bioactive compounds.
Special attention is given to:
The interaction between the food matrix and bioactive compounds
The stability of amino acids, CoQ10, and carotenoids
The selection of delivery formats compatible with clinical trials
This formulation-driven approach is essential to translate technological innovation into meaningful nutritional exposure.
Why it matters: bioavailability and compliance in human studies
In human clinical research, bioavailability and participant compliance are closely linked. UCLouvain therefore integrates formulation optimisation with practical considerations such as palatability, tolerance, and ease of consumption.
By ensuring high compliance, the project can generate reliable and robust clinical data, which are essential to demonstrate health effects and support future applications.
Demonstrating health effects: a multicentric clinical study
UCLouvain plays a key role in the design and implementation of a multicentric human clinical study evaluating optimized purple bacteria–based formulations.
This study aims to assess their impact on nutritional, metabolic, and oxidative stress–related biomarkers, providing strong scientific evidence for the health potential of these innovative ingredients.
What comes next
Next steps include further formulation refinement and the generation of high-quality clinical data to support the development of effective, compliant, and scientifically validated purple bacteria–based nutritional solutions within Purple4Life.
By
Valerie Dormal (UCLouvain)
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